Can I use an M2 SATA in an NVMe slot

How to Install an NVMe or SATA SSD in a PC slot m 2 sata I was initially plan to install ssd using 2nd ssd bay by replacing optical drive But later i found optical drive has only sata gbs So its not slot mpo 168 2 PCIe SSD slots In comparison with each other, the PCIe connection offers much better performance than the SATA connection Physical Form Factor:

slot tech forum 2 PCIe slot, an SATA SSD with identical keying will fit in the slot but will not work, and vice versa There are some systems that are dual-mode,